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BlueGene Biotech P01I0345 Human Interferon gamma (IFNγ) Protein, Recombinant

  • Immunology
  • Cancer
  • Stem cells
  • Immunology_copy20241119
  • Cancer_copy20241119
  • Stem cells_copy20241119

Interferon gamma (IFNγ) can also be called IFG; IFI; IMD69

Products

Specifications Of P01I0345 Human Interferon gamma (IFNγ) Protein, Recombinant

Product Information

Catalog Number

P01I0345

Package Size

10ug/50ug/500ug/1mg

Other Names

IFG; IFI; IMD69

Protein & NCBI Number

P01579、NM_000619.3

Host

E.coli

Express Region

Met1-Gln166

Protein Sequence

MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSD

VADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNV

KFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFR

GRRASQ

Molecular Weight

The protein consists of 292 amino acids (including the fusion tag), with a predicted
molecular weight of 33.7 kDa, which matches the actual molecular weight.

Fusion Tag

6×His-SUMO (N-terminus)

Purity

≥95% SDS-PAGE

Physical Property

Liquid

Components

0.01M PBS+20% glycerol, sterile solution.

Storage & Stability

After aliquoting, the stability of the samples can be maintained for up to 6 months
at -20°C to -80°C, avoiding repeated freeze-thaw cycles.

Applications

Antibody preparation, immunoassay (ELISA, WB), subcellular localization and
interaction protein identification, etc.

Lead Time

5 to 10 business days;

2 to 3 days for stock products


Background

IFNG gene encodes a soluble cytokine that is a member of the type II interferon class. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. It has the functions of anti-virus, affecting cell growth and differentiation, anti-tumor, anti parasite and immune regulation.

Interferon- γ (interferon-gamma, IFN- γ) It is a cytokine mainly secreted by activated T cells and NK cells under the stimulation of mitogen and specific antigen. It is also a soluble glycoprotein, heat-resistant and acid, which is unstable at pH = 2. IFN- γ It can not only affect the cellular functions including anti-virus, anti swelling, cancer cell growth and differentiation, but also play an important role in immune regulation, such as promoting the synthesis of rRNA, promoting the expression of class I and class II histocompatibility antigens, and regulating the functional activity of homologous K cells, NK cells and macrophages. IFN- γ It also has antiviral activity, which is lower than type I, but it has strong immune regulation and anti cell proliferation, so it is also called immune interferon.


Specifications Of P01I0345 Human Interferon gamma (IFNγ) Protein, Recombinant_copy20241119

Product Information

Catalog Number

P01I0345

Package Size

10ug/50ug/500ug/1mg

Other Names

IFG; IFI; IMD69

Protein & NCBI Number

P01579、NM_000619.3

Host

E.coli

Express Region

Met1-Gln166

Protein Sequence

MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSD

VADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNV

KFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFR

GRRASQ

Molecular Weight

The protein consists of 292 amino acids (including the fusion tag), with a predicted
molecular weight of 33.7 kDa, which matches the actual molecular weight.

Fusion Tag

6×His-SUMO (N-terminus)

Purity

≥95% SDS-PAGE

Physical Property

Liquid

Components

0.01M PBS+20% glycerol, sterile solution.

Storage & Stability

After aliquoting, the stability of the samples can be maintained for up to 6 months
at -20°C to -80°C, avoiding repeated freeze-thaw cycles.

Applications

Antibody preparation, immunoassay (ELISA, WB), subcellular localization and
interaction protein identification, etc.

Lead Time

5 to 10 business days;

2 to 3 days for stock products


Background

IFNG gene encodes a soluble cytokine that is a member of the type II interferon class. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. It has the functions of anti-virus, affecting cell growth and differentiation, anti-tumor, anti parasite and immune regulation.

Interferon- γ (interferon-gamma, IFN- γ) It is a cytokine mainly secreted by activated T cells and NK cells under the stimulation of mitogen and specific antigen. It is also a soluble glycoprotein, heat-resistant and acid, which is unstable at pH = 2. IFN- γ It can not only affect the cellular functions including anti-virus, anti swelling, cancer cell growth and differentiation, but also play an important role in immune regulation, such as promoting the synthesis of rRNA, promoting the expression of class I and class II histocompatibility antigens, and regulating the functional activity of homologous K cells, NK cells and macrophages. IFN- γ It also has antiviral activity, which is lower than type I, but it has strong immune regulation and anti cell proliferation, so it is also called immune interferon.


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BlueGene Biotech Product Show_copy20241119

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